Refereed Publications

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Fragis, M., A. Murayyan, S. Neethirajan. 2018. Cytotoxic activity and anti-cancer potential of Ontario grown onion extracts against breast cancer cell lines.  Functional Foods in Health & Disease 8(3): 159-174. (Link

Weng, X., S. R. Ahmed, S. Neethirajan. 2018. A nanocomposite-based biosensor for bovine haptoglobin on a 3D paper-based analytical device. Sensors and Actuators B: Chemical  Doi: 10.1016/j.snb.2018.03.061 (Link

Neethirajan, S., V. Ragavan, X. Weng. 2018. Biosensors for Sustainable Food Engineering: Challenges and Prospective. Biosensors. (biosensors-270845) (Link)

Neethirajan, S., X. Weng, A. Tah. 2018. Nano-Biosensor Platforms for Detecting Food Allergens - New Trends. Sensing and Bio-Sensing Research. Doi: 10.1016/j.sbsr.2018.02.005 (Link)

Ahmed, S.R., S. Neethirajan. 2018. Chiral MoS2 Quantum Dots: Dual-Mode Detection Approaches for Avian Influenza Viruses. Global Challenges. doi:10.1002/gch2.201700071 (Link)

Ahmed, S.R., J. Mogus, R. Chand, E. Nagy, S. Neethirajan. 2018. Optoelectronic fowl adenovirus detection based on local electric field enhancement on graphene quantum dots and gold nanobundle hybrid. Biosensors & Bioelectronics  (Link

Tuteja, S., S. Neethirajan. 2018. Exploration of 2-dimensional bio-functionalized phosphorene nanosheets (Black Phosphorous) for label free haptoglobin electro-immunosensing applications. Nanotechnology (Link

Neethirajan, S., K.V. Ragavan, X. Weng. 2018. Agro-defense: Biosensors for food from healthy crops and animals.  Trends in Food Science & Technology  doi: 10.1016/j.tifs.2017.12.005   (Link

Ragavan, K.V. S. Kumar, S. Swaraj, S. Neethirajan. 2018. Advances in biosensors and optical assays for diagnosis and detection of malaria. Biosensors & Bioelectronics  (link

Chand, R., Y. L. Wang, D. Kelton, S. Neethirajan. 2018. Isothermal DNA amplification with functionalized graphene and nanoparticle assisted electroanalysis for rapid detection of Johne’s disease. Sensors & Actuators B: Chemical (Link)

Jiang, X., H. Lin, J. Shi, S. Neethirajan, Y. Lin, Y. Chen, H. Wang, Y. Lin. 2018. Effects of a novel chitosan formulation treatment on quality attributes and storage behaviour of harvested litchi fruit. Food Chemistry  (Link

Tuteja, S., C. Ormbsy, S. Neethirajan. 2018. Non-invasive Label-free Detection of Cortisol and Lactate using Graphene Embedded Screen-printed Electrode. Nano-Micro Letters (Link



Weng, X., S. Neethirajan. 2017. Paper-based microfluidic aptasensor for food safety. Journal of Food Safety. doi: 10.1111/jfs.12412 (Link) (pdf) 

Berthelot, R., S. Neethirajan. 2017. Nanoscale imaging approaches to quantifying the electrical properties of pathogenic bacteria. Biomedical Physics & Engineering Express doi: 10.1088/2057-1976/aa91f8 (Link) (pdf)  

Ahmed, S.R., E. Nagy, S. Neethirajan. 2017. Self-assembled star-shaped chrioplasmonic gold nanoparticles for ultrasensitive chiro-immunosensor of viruses. RSC Advances doi: 10.1039/c7r07175b (Link)  

Weng, X., S. Neethirajan. 2017. Aptamer-based Fluorometric Determination of Norovirus Using a Paper-based Microfluidic Device. Microchimica Acta DOI 10.1007/s00604-017-2467-x  (link

Tuteja, S., S. Neethirajan. 2017. A highly efficient 2D exfoliated metal dichalcogenide for on-farm rapid monitoring of non-esterified fatty acid. Chemical Communications doi: 10.1039/C7CC04894G (Link

Tuteja, S., T. Duffield, S. Neethirajan. 2017. Graphene based Multiplexed disposable electrochemical biosensor for on-farm rapid monitoring of NEFA and βHBA Dairy biomarkers. Journal of Materials Chemistry B doi: 10.1039/C7TB01382E  (Link)  (PDF) 

Panesar, S., X. Weng, S. Neethirajan. 2017. Towards point-of-care diagnostics of breast cancer: development of an optical biosensor using quantum dots. IEEE Sensors Letters doi: 10.1109/LSENS.2017.2727983  (Link)  (PDF) 

Tuteja, S., T. Duffield, S. Neethirajan. 2017. Liquid Exfoliation of MoS2 nanosheets and their utilization as a label-free electrochemical immunoassay for subclinical ketosis. Nanoscale doi: 10.1039/C7NR04307D  (Link) (PDF) 

Neethirajan, S., S. Tuteja, Huang, S.T, D. Kelton. 2017. Recent advancement in biosensors technology for animal and livestock health management. Biosensors and Bioelectronics doi: 10.1016/j.bios.2017.07.015 (Link). (PDF

Berthelot, R., K. Doxsee, S. Neethirajan. 2017. Electroceutical approach for impairing the motility of pathogenic bacterium using microfluidic platform Micromachines 8(7), 207: 1-11 (link) (PDF)

Ahmed, S.R., J. C. Corredor, E. Nagy, S. Neethirajan. 2017. Amplified visual immunosensor integrated with nanozyme for ultrasensitive detection of avian influenza virus Nanotheranostics  doi: 10.7150/ntno.20758 (link) (PDF)

Chand, R., S. Neethirajan. 2017. Microfluidic platform integrated with graphene-gold nano-composite aptasensor for one-step detection of norovirus. Biosensors and Bioelectronics doi: 10.1016/j.bios.2017.06.026 (link) (PDF)

Neethirajan, S., S.R. Ahmed, R. Chand, J. Buozis, E. Nagy. 2017. Recent Advances in biosensor development for foodborne virus detection. Nanotheranostics doi:10.7150/ntno.20301 (link) (PDF)

Manibalan, K., V. Mani, P. Chang, C. Huang, S. Huang, K. Marchlewicz, S. Neethirajan. 2017. Electrochemical latent redox ratiometric probes for real-time tracking and quantification of endogeneous hydrogen sulfide production in living cells. Biosensors and Bioelectronics 96, 233-238. (link) (PDF)

Jang, H., S.R. Ahmed, S. Neethirajan. 2017. GryphSens: A smartphone-based portable diagnostic reader for the rapid detection of progesterone in milk. Sensors 17(5), 1079' doi: 10.3390/s17051079 (link) (PDF) 

Weng, X., S. Neethirajan. 2017. Ensuring food safety: Quality monitoring using microfluidics. Trends in Food Science & Technology  65, 10-22. (link)  (PDF) 

Murayyan, A., C. Manohar, G. Hayward, S. Neethirajan. 2017. Antiproliferative activity of Ontario grown onions against colorectal adenocarcinoma cells. Food Research International 96, 12-18. (link) (PDF)

Ahmed, S.R., J. Kim, V.T. Tran, T. Suzuki, S. Neethirajan, J. Lee. 2017. In situ self assembly of gold nanoparticles on hydrophilic and hydrophobic substrates for influenza virus-sensing platform. Scientific Reports (link)  (PDF)

Chand, R., D. Han, S. Neethirajan, Y. Kim. 2017. Detection of protein kinase using an aptamer on a microchip integrated electrolyte-insulator-semiconductor sensor. Sensors and Actuators B: Chemical   doi:10.1016/j.snb.2017.02.140 (link) (PDF)

Berthelot, R., S. Neethirajan. (2017). Harnessing electrical energy for anti-biofilm therapies: effects of current on cell morphology and motility. Journal of Experimental Nanoscience, (link)(PDF)

Manohar, C., J. Xue, A. Murayyan, S. Neethirajan, J. Shi. Antioxidant activity of polyphenols from Ontario grown onion varieties using pressurized low polarity water technology. Journal of Functional Foods 31, 52-62  (link) (PDF

Huang, S., B. Guild, S. Neethirajan, P. Therrien, L. Lim, K. Warriner. 2017. Antimicrobial coatings for controlling Listeria monocytogenes based on polylactide modified with titanium dioxide and illuminated with UV-A. Food Control 73(B): 421-425 (link) (PDF)



Neethirajan, S. 2016. Recent advances in wearable sensors for animal health management. Sensing and Bio-Sensing Research. doi:10.1016/j.sbsr.2016.11.004  (link

Huang, S., B. Guild, S. Neethirajan, P. Therrien, L. Lim, K. Warriner. 2017. Antimicrobial coatings for controlling Listeria monocytogenes based on polylactide modified with titanium dioxide and illuminated with UV-A. Food Control (link

Weng, S., S. Neethirajan. (2016). A microfluidic biosensor using graphene oxide and aptamer-functionalized quantum dots for peanut allergen detection. Biosensors and Bioelectronics. Doi: 10.1016/j.bios.2016.05.072 (link)

Veerapandian, M., R. Hunter, S. Neethirajan. (2016). Dual immunosensor based on methylene blue-electroadsorbed graphene oxide for rapid detection of influenza virus antigen. Talanta. doi: 10.1016/j.talanta.2016.04.047 (link)

Weng, X., S. Neethirajan, A. Vogt. (2016). Single cell chemotactic responses of Helicobacter pylori to urea in a microfluidic chip. Applied Sciences. 6(5), 139; doi:10.3390/app6050139 (link)

Dhayakaran, R., X. Weng, S. Neethirajan. (2016). Investigation of the anitmicrobial activity of soy peptides by developing a high throughput drug screening assay. Biochemistry and Biophysics Reports. Doi:10.1016/j.bbrep.2016.04.001 (link)

Weng, X., G. Gaur, S. Neethirajan. (2016). Rapid detection of food allergens by microfluidics ELISA-based optical sensor . Biosensors. DOI: 10.3390/bios6020024 (link) (PDF)

Panesar, S., S. Neethirajan. (2016). Microfluidics: rapid diagnosis for breast cancer. Nano-Micro Letters. DOI:10.1007/s40820-015-0079-8 (link) (PDF)

Veerapandian, M., R. Hunter, S. Neethirajan. (2016). Ruthenium dye sensitized graphene oxide electrode for on-farm rapid detection of beta-hydroxybutyrate. Sensors and Actuators B: Chemical. DOI: 10.1016/j.snb.2016.01.028 (link) (PDF)


Preiss, L., S. Neethirajan. (2015). Single Cells of Pseudomonas aeruginosa Exhibit Electrotaxis and Durotaxis Behaviours. biorxiv (link)

Mungroo, N., G. Oliveira, S. Neethirajan. (2015). SERS based point-of-care detection of food-borne pathogens  Microchimica Acta. DOI: 10.1007/s00604-015-1698-y  (link) (PDF)

Veerapandian, M., R. Hunter, S. Neethirajan. (2015). Lipoxygenase-modified Ru-bby / graphene oxide: Electrochemical biosensor for on-farm monitoring of non-esterified fatty acid. Biosensors and Bioelectronics. DOI: 10.1016/j.bios.2015.11.058 (link) (PDF)

Veerapandian, M., S. Neethirajan. (2015). Graphene oxide chemically decorated with Ag-Ru/chitosan nanoparticles: Fabrication, Electrode Processing and Immunosensing Property. RSC Advances. Doi:10.1039/C5RA15329H  (link) (PDF)

Weng, X., J. Niekerk, S. Neethirajan, K. Warriner. (2015). Characterization of antimicrobial efficacy of photocatalytic polymers against food-borne biofilms. LWT Food Science and Technology Journal. DOI: 10.1016/j.lwt.2015.11.063 (link) (PDF)

Chen, L., L. Daikuara, S. Neethirajan. (2015). Label-free NIR-SERS discrimination and detection of foodborne bacteria by in-situ synthesis of Ag colloids. Journal of Nanobiotechnology. DOI: 10.1186/s12951-015-0106-4 (link) (PDF)

Wright, E., S. Neethirajan, X. Wang. (2015). Microfluidic wound model for studying the behaviours of Pseudomonas aeruginosa in polymicrobial biofilms. Biotechnology and Bioengineering. doi:10.1002/bit.25651 (link) (PDF)

Weng, X., L. Chen, S. Neethirajan, T. Duffield. (2015). Development of quantum-dots based biosensor towards on-farm detection of subclinical ketosis. Biosensors and Bioelectronics. 72(15): 140-147 (link) (PDF)

Dhayakaran, R., S. Neethirajan, J. Xue, J. Shi. (2015). Characterization of Antimicrobial Efficacy of Soy Isoflavones Against Pathogenic Biofilms.  LWT Food Science and Technology. (Accepted) (link) (PDF)

Suresh, A., S. Neethirajan (2015). Real-time 3D visualization and quantitative analysis of internal structure of wheat kernels.  Journal of Cereal Science (In Press) doi:10.1016/j.jcs.2015.03.006 (link) (PDF)

Chen, L., S. Neethirajan. (2015). A homogeneous fluorescence quenching based assay for specific and sensitive detection of Influenza virus A Hemagglutinin antigen. Sensors 15(4): 8852-8865. (link) (PDF)

Birkenhauer, E., S. Neethirajan. (2015). A Double-Edged Sword: The Role of VEGF in Wound Repair and Chemoattraction of Opportunist Pathogens. International Journal of Molecular Sciences. doi:10.3390/ijms16047159  (link) (PDF)

Griffith, A., S. Neethirajan, K. Warriner (2015). Development and evaluation of silver zeolite antifouling coatings on stainless steel for food contact surfaces. Journal of Food Safety. doi: 10.1111/jfs.12181 (link) (PDF)

Weng, X., W. Zhao, S. Neethirajan. (2015). Microfluidic biosensor for β-Hydroxybutyrate (βHBA) determination of subclinical ketosis diagnosis. Journal of Nanobiotechnology DOI 10.1186/s12951-015-0076-6  (link) (PDF)



Mungroo, N.A., S. Neethirajan. (2014). Biosensors for the detection of antibiotics in poultry industry. Biosensors doi: 10.3390/bios4040472  (link) (PDF)

Birkenhauer, E., S. Neethirajan. (2014). Characterization of electrical surface properties of mono- and co-cultures of Pseudomonas aeruginosa and methicillin-resistant Staphylococcus aureus using Kelvin probe force microscopy. RSC Advances DOI: 10.1039/C4RA07446G (link) (PDF)

Warriner, K., S.M. Reddy, A. Namvar, S. Neethirajan. (2014). Developments in Nanoparticles for Use in Biosensors to Assess Food Safety and Quality. Trends in Food Science and Technology. DOI: 10.1016/j.tifs.2014.07.008 (link) (PDF)

Birkenhauer, E., S. Neethirajan. (2014). Surface Potential Measurement of Bacteria Using Kelvin Probe Force Microscopy. Journal of Visualized Experiments.  doi:10.3791/52327 (link) (PDF)

Neethirajan, S., M.A. Clond, A. Vogt (2014). Medical Biofilms - Nanotechnology Approaches. Journal of Biomedical Nanotechnology. 10:  doi:10.1166/jbn.2014.1892 (link) (PDF)

DiCicco, M., S. Neethirajan. (2014). An in-vitro microfluidic gradient generator platform for antimicrobial testing. Biochip Journal doi:10.1007/s13206-014-8406-6 (link) (PDF)

DiCicco, M., S. Neethirajan, S. Weese, A. Singh. (2014). In vitro synergism of fosfomycin and clarithromycin antimicrobials against methicillin-resistant Staphylococcus pseudintermediusBMC Microbiology 14:129 doi:10.1186/1471-2180-14-129 (link) (PDF)

Birkenhauer, E., S. Neethirajan, S. Weese. (2014). Collagen and hyaluronan at wound sites influence early polymicrobial biofilm adhesive events. BMC Microbiology. doi:10.1186/1471-2180-14-191 (link) (PDF)

DiCicco, M., S. Weese, S. Neethirajan, J. Rousseau, A. Singh. (2014). Fosfomycin susceptibility of methicillin-resistant Staphylococcus pseudintermedius. Research in Veterinary Science. doi: 10.1016/j.rvsc.2014.02.004. (link) (PDF)

Wright, E., S. Neethirajan, K. Warriner, S. Retterer. B. Srijanto. (2014). Single cell swimming dynamics of Listeria Monocytogenes using a nanoporous microfluidic platform. Lab on a Chip DOI: 10.1039/c3lc51138c (link) (PDF)

Terry, J., S. Neethirajan. (2014). A novel microfluidic wound model for testing antimicrobial agents against Staphylococcus pseudintermedius biofilms. Journal of Nanobiotechnology 12:1  doi:10.1186/1477-3155-12-1 (link) (PDF)



Yangquanwei, Z., S. Neethirajan, C. Karunakaran. (2013). Cytogenetic analysis of quinoa chromosomes using nanoscale imaging and spectroscopy techniques. Nanoscale Research Letters. Nov 6;8(1):463. doi: 10.1186/1556-276X-8-463. (link(PDF)

Neethirajan, S., M. DiCicco. (2013). Atomic Force Microscopy Study of the Antibacterial Effect of Fosfomycin on Methicillin-Resistant Staphylococcus Pseudintermedius. Applied Nanoscience. DOI 10.1007/s13204-013-0256-3 (link) (PDF)

Fletcher, M., M. Biglarbegian, S. Neethirajan. (2013). Intelligent System Design for Bionanorobots in Drug Delivery. Cancer Nanotechnology. DOI 10.1007/s12645-013-0044-5 (link) (PDF)



Kumar, A., D. Karig, R. Acharya, S. Neethirajan, P.P. Mukherjee, S. Retterer, M.J. Doktycz. (2012). Microscale confinement features can affect biofilm formation. Microfluidics and Nanofluidics. DOI 10.1007/s10404-012-1120-6. (link) (PDF)

DiCicco, M., S. Neethirajan, A. Singh, S. Weese. (2012). Efficacy of clarithromycin on biofilm formation of methicillin-resistant staphylococcus pseudintermedius. BMC Veterinary Research (link) (PDF)

Neethirajan, S., T. Ono, E. Masayoshi. (2012). Characterization of catalytic chemical vapor deposited SiCN thin film coatings. International Nano Letters (link) (PDF)

Neethirajan, S., K. Tsukamoto, S. Sugiyama. (2012). Ultrastructural analysis of buckwheat starch components using atomic force microscopy. Journal  of Food Science 77, N2-N7. (link) (PDF)


2006 - 2011

Neethirajan, S., T. Hirose, K. Tsukamoto, J. Wakayama, H. Kanehara, S. Sugiyama. (2011). Karyotype analysis of buckwheat using atomic force microscopy. Microscopy and Microanalysis 17, 572-577. (link) (PDF)

Neethirajan, S., I. Kobayashi, M. Nakajima, D. Wu, S. Nandagopal, F. Lin. (2011). Microfluidics for food, agriculture and biosystems industries. Lab on a Chip 11, 1574-1586. (link)  (PDF)

Ramalingam, G., S. Neethirajan, D.S. Jayas, N.D.G. White. (2010) Characterization of the influence of moisture content on the morphological features of single wheat kernels using machine vision. Applied Engineering in Agriculture 27, 403-409. (link) (PDF)

Neethirajan, S., M.S. Freund, C.Shafai, D.S. Jayas, D.J. Thomson, N.D.G. White. (2010) Development of carbon dioxide sensor for grain quality monitoring. Biosystems Engineering doi:10.1016/j.biosystemseng.2010.05.002. (link) (PDF)

Neethirajan, S., D.S. Jayas. (2010) Nanotechnology for food, and bioprocessing industries. Food and Bioprocess Technology [invited paper] DOI 10.1007/s11947-010-0328-2. (link) (PDF)

Neethirajan, S., R. Gordon, L. Wang. (2009) Potential of silica bodies (Phytoliths) for nanotechnology [invited paper] Trends in Biotechnology 27(8): 461-467. (link) (PDF)

Neethirajan, S., D.S. Jayas, S. Sadistap. (2008) Carbon dioxide (CO2) sensors for the agricultural and food industry - A Review. Food and Bioprocess Technology 2(2): 115-121.(link) (PDF)

Neethirajan, S., D.J. Thomson, D.S. Jayas, N.D.G. White. (2008) Characterization of the surface morphology of durum wheat starch granules using atomic force microscopy, Microscopy Research and Technique, 71(2): 125-132.(link) (PDF)

Neethirajan, S., D.S. Jayas, N.D.G. White, H. Zhang. (2008) Investigation of 3D geometry of bulk wheat and pea pores using X-ray computed tomography images, Computers and Electronics in Agriculture, 63(2): 104-111.(link) (PDF)

Neethirajan, S., D.S. Jayas. (2008) Analysis of pore network in three-dimensional (3D) in grain bulk using X-ray CT images, Transport in Porous Media, 73(3): 319-332.(link) (PDF)

A.R. Tahir, S. Neethirajan, D.S. Jayas, M. Shahin, S.J. Symons, N.D.G. White. (2007) Evaluation of the effect of moisture content on cereal grains by digital image analysis, Food Research International, 40(9): 1140-1145.(link) (PDF)

Neethirajan, S., D.S. Jayas, C. Karunakaran. (2007) Dual energy X-ray image analysis for classifying vitreousness in durum wheat, Post Harvest Biology and Technology, 45(3): 381-384.(link) (PDF)

Neethirajan, S., D.S. Jayas N.D.G. White. (2007). Detection of sprouted wheat kernels using soft X-ray image analysis, Journal of Food Engineering, 81(3): 509-513.(link) (PDF)

Neethirajan, S., C. Karunakaran, D.S. Jayas, N.D.G. White. (2007). Detection techniques for stored product pests in grain, Food Control, 18(2): 157-162.(link) (PDF)

Neethirajan, S., C. Karunakaran, S. Symons, D.S. Jayas. (2006) Classification of vitreousness in durum wheat using X-rays and transmitted light images, Computers and Electronics in Agriculture, 53(1): 71-78.(link) (PDF)

Neethirajan, S., C. Karunakaran, D.S. Jayas, N.D.G. White. (2006) X-ray computed tomography image analysis to explain the airflow resistance differences in grain bulks, Biosystems Engineering, 94(4): 545-555.(link) (PDF)

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