Globalization and ecological pressures have increased the emergence of novel infections and global pandemics in poultry sector. This means that not only livestock such as poultry and egg laying birds are at increasing risk of contracting new and difficult to control diseases, but the people who care for them are as well. This is a game changer brought on by the speed of evolution of disease organisms. To meet the current and emerging challenges of poultry and egg laying birds’ disease surveillance, diagnostics and control, it is imperative that a paradigm shift occurs in how diseases are identified. This shift involves predicting diseases even before it occurs and preventing them through enhanced surveillance tools. Canadian poultry and livestock sector is under heavy pressure to improve its biosecurity protocols and enhance animal welfare. Canadian Food Inspection Agency is seeking new tools to enable rapid, real-time and on-farm monitoring of diseases, disease causing factors, and record keeping. The development of affordable; nanotechnologies based wireless networks that can be used for accurate real-time monitoring of the poultry farm environment is being addressed.  The BioNanolab of the University of Guelph has developed a real-time warning system for monitoring multiple environmental factors such as carbon dioxide and ammonia concentrations, temperature, humidity, water level, and activity of the chicken birds in the poultry farm using a user-friendly mobile ‘App’ and a wireless telemetry network architecture. The development of a framework and integration of wireless sensors and mobile system network to control and remotely monitor environmental parameters in the poultry farm provides as a promising biosecurity tool.